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Allergy to house dust mite appeared to be a significant feature in the disease pathogenesis, and it is likely that this is associated with modifications to traditional life style due to the introduction of blankets and changes in sleeping habits, which promote a more fertile environment for growth and multiplication of mites (Dowse et al., 1985)

Strong oxidants such as hydrogen peroxide (H 2 O 2 ) instead readily modify protein thiols beyond reversible redox states, to form sulfinic (-SO 2 H) and sulfonic acids (-SO 3 H), thus preventing conversion into the disulfide-linked pathological species dsNNTTR

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